Foreign experience
  • 2017 № 3 The possibility of adapting European clinical and economic models for use in the Russian routine practice to calculate the treatment of patients with diabetes mellitus type 2

    The cost of the type 2 diabetes mellitus (DM2) treatment with dapagliflozin as a first-line drug, its subsequent combination with metformin and then switching to insulin therapy, were 297 321 068 rubles. This calculation based on the prospective modelling with a 25 year prognosis horizon in the cohort of 1,000 patients. In case of the first-line saxagliptin application, its following combination with metformin and then switching to insulin therapy, the costs were 297 733 828 rubles, that is at 412,760 rubles more than first-line dapagliflozin strategy. A cost-effectiveness analysis of the first-line dapagliflozin strategy in comparing with the saxagliptin treatment is not highly sensitive to changes in the price that are within 10%. In this range of price changes, the dapagliflozin strategy can be considered even more cost-effective achieving 141.38 rubles for QALY gained with an increase in the price of dapagliflozin by 10% and 244.05 rubles / QALY, while the price of saxagliptin decreases by 10%.

    Authors: Zelenova O. V. [4] Zhilina V. V. [3] Kreknina E. A. [5] Sannikov A. I. [2] Belyakova N. V. [3]

    Tags: cost-effectiveness2 diabetes mellitus type 2 (dm2)1 direct costs5 sensitivity analysis1 treatment strategy1

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  • Management in healthcare
  • 2017 № 10 Procurement management of major resources expenditure of the medical organization by creating a matrix of consumption and planning

    Effective and efficient use of budget one of the priority tasks facing the chief physicians. Nomenclature of drugs in cancer clinics has dozens of INNs and hundreds of trade names, which greatly complicates the work of purchasing departments. Maintaining an optimal balance between the income and consumption of goods is an important task of every medical institution. To achieve this goal requires a clearly established system of inventory management that will optimize and effectively predict purchases in subsequent periods. The analysis allows for closer examination of the consumption budget of the institution for each commodity group, the INNs and the ATC groups and build a matrix of inventory given the importance and deman

    Authors: Zelenova O. V. [4] Kreknina E. A. [5] Sannikov A. I. [2] Danilov V. M. [1] Abramov S. I. [1]

    Tags: abc analysis2 atc classification1 medical stores and drug inventory1 purchase of medicines1

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