2015 № 10 Biomedicine priorities in the focus of the practical assessment of the prospects applications (Federal Research)
Using genome-sequencing as an example there are analysed risks when choosing priorities for science and technologies development in Russia, based only on the analysis of trends in development of global biomedicine, but not factoring resource provision of the direction. It is demonstrated that in today’s Russia there is a lack of sufficient numbers of competent doctors-genetics. The volume of core courses in medical universities (36 hours) in Russian Federation is inadequate to the intensity of the development of this direction and growth in numbers of genetic diseases. Modern domestic park of sequenators is represented by the equipment of early generation, using which prevents it to meet the world standards of research in the area of genome medicine. In practice the technology of genome sequencing is not widely used in the health care due to high costs of the diagnostics procedures. There is a conclusion drawn about unviability of choice as a priority direction of development, which doesn’t have the personnel and instrumental provision as well as demand in the real sector of economy.
2018 № 8 Causes and models of transformation of strategies for technological development of transnational pharmaceutical companies
During the last ten years, the largest pharmaceutical manufacturers significantly changed their approaches to the formation of their own strategies for capturing and retaining the leading positions in global markets. One of the key prerequisites was a decline in the return on investment in R & D: if in 2010 among the top 12 pharmaceutical companies of the world this indicator was 10.1%, then in 2017 it fell to 3.2%. At the same time, the cost of devel¬oping and launching new medicines has increased: from $1.2 billion to $2 billion in 2010–2017. The article analyzes the main reasons for the transformation of the strategies of the Big Pharma companies. It has been suggested that, in the context of a decline in payback in R & D, increased competition, a fall in public expen¬diture on the purchase of pharmaceuticals, and tightening of regulatory requirements, it is advisable for domestic companies to reorient the creation of corporate venture funds and investing in start-ups, and actively use the mergers and acquisitions strategy
2018 № 6 The Development of post-genomic technologies in the Russian Federation: barriers and risks
The risks of implementation of the complex scientific and technological program “Postgenomic technolo¬gies: from genetic editing to synthetic biology” in the Russian Federation are Considered. As barriers for the full life cycle projects related to genomic editing technologies, the following are highlighted: lack of a sufficient number of personnel, low competitiveness of domestic scientific and technological reserves, lack of modern instrument base, lack of industrial partners, as well as problems of legal regulation of genetic engineering in the Russian Federation. The analysis of the global competitive landscape in the field of genomic editing technologies is carried out
2016 № 10 The history of the development of breakthrough biomedical areas: lessons for Russia
An analysis was conducted of a model for accelerating the life cycle of research and development, as well as temporary parameters for transforming fundamental industrial perspective using an example of reprogramming technologies for obtaining induced pluripotent stem cells. It is shown that the key role in accelerating the industrial life cycle is played by the fast growing medium high technological companies and large industrial companies, interested in diversification of their business strategies. There has been recorded a significant deceleration in the development of the life cycle in this area in Russia, and its causes have been identified.
2016 № 9 History of the development of breakthrough biomedical areas: lessons for Russia
On the example of development of technologies of reprogramming to obtain induced pluripotent stem cells estimated timelines for the transformation of the results of breakthrough fundamental research into commercial high-tech product in Japan, USA and Russia. The conclusion is that a key role in accelerating the life cycle of research and development play a growing high-tech companies and large industrial companies interested in diversifying their business strategies. It is stated a critical lag of the development of life cycle studies in this field in Russia and investigates its causes.
2015 № 7 Evaluation of contributions of specific areas of clinical medicine to Russian integral publication flow, indexed in Web of Science and Scopus
The deadline for evaluating achievements by Order № 599 of the Russian President dated 7 May 2012, in accordance to which the share of Russian researcher’s publications among all publications of international scientific journals, indexed in the Web of Science data base, should reach 2,44% by 2015, is fast approaching. The article evaluates the contribution of specific areas of clinical medicine to integral publication flow in Russia, indexed in Web of Science in the period between 2011 to 2015. It is demonstrated that despite the efforts of the professional medical community directed on increasing the publication activity in international segment, the share of Russian publications remain at a low level. The issue of reflecting research findings in international journals is particularly critical for Russian surgeons, dentists, orthopaedists and otolaryngologists.
2015 № 6 Possible methodological approaches to reviewing Russian clinical medicine journals in order to be published in Russian science citation index on the platform of Web of science
There was analysed a methodology for reviewing thousands of leading Russian journals in order to get published in the National Science Citation Index — Russian Science Citation Index in a form of a separate base created on the platform of Web of Science, which is used by coordinators of the project. There was suggested the methodology for reviewing domestic scientific journals in order to be included in the RSCI, which is formed on the basis of establishment of quotas of journals by subject areas in accordance with disciplinary structure of world science, as well as for identifying the most productive and dynamicly developed scientific disciplines in the frames of separately chosen subject area (using an example of clinical medicine).
2015 № 3 Medical sciences after optimizing the chain of dissertation councils in Russia
The article explored outcomes of optimizing a network of dissertation councils in Russia in the period between 2013 and 2015 years.The subject structure of world science was compared with anticipated after optimization disciplinary structure of highly qualified Russian scientific personnel body. To make the comparison complete, there was evaluated the gravity of publication flow volume per certain subjects in data bases like Web of Science and the contribution of certain related areas in forming research frontlines according to data of Essential Science Indicators. It was factually proven that project's realization contributes to the process of balancing out the structure of reproduced body of highly qualified personnel in Russia and of the world's science subject structure. In addition to that, it was noted that by the end of 2015 year Russia will witness a groundlessly low share of dissertation councils in medicine and similarly groundlessly in the context of global science development trends a high share of councils in economics sciences.